Christopher Pike vs Caitlyn: who would win?

Caitlyn favored — Favored (~65%)

Christopher Pike · Star Trek · Normal

Tier
10-A, up to 8-C
Attack Potency
Below Average Human Level, up to Building Level
Speed
Athletic Human, up to Speed Of Light
Durability
Athlete Level

Caitlyn · League of Legends · Resistance

Tier
10-B, up to HIGH 6-C
Attack Potency
City Level, up to Universe Level+
Speed
Average Human, up to Subsonic
Durability
Wall Level

A heuristic estimate from normalized VS Battles Wiki stats: tier, attack potency, speed and durability.