Vaccine Man vs Akemura Soga: who would win?

Vaccine Man favored — Slight edge (~55%)

Vaccine Man · One-Punch Man · Base

Tier
7-B
Attack Potency
City Level+
Speed
Unknown
Durability
City Level+

Akemura Soga · Kagurabachi · Base

Tier
7-B
Attack Potency
City Level
Speed
Sub-Relativistic
Durability
City Level

A heuristic estimate from normalized VS Battles Wiki stats: tier, attack potency, speed and durability.