The Great Holy Spirit vs Lux Imperator: who would win?

Lux Imperator favored — Slight edge (~55%)

The Great Holy Spirit · Tensei Shitara Slime Datta Ken · Base

Tier

1-C

Attack Potency

Complex Multiverse Level

Speed

Omnipresent

Durability

Complex Multiverse Level

Lux Imperator · Doctor Who · Base

Tier

HIGH 1-C

Attack Potency

High Complex Multiverse Level

Speed

Below Average Human, up to Nigh-Omnipresent

Durability

High Complex Multiverse Level

A heuristic estimate from normalized VS Battles Wiki stats: tier, attack potency, speed and durability.