Madoka Kaname vs Vecna: who would win?

Madoka Kaname favored — Slight edge (~55%)

Madoka Kaname · Puella Magi Verse · Ultimate Madoka

Tier

2-A

Attack Potency

Multiverse Level+

Speed

Omnipresent

Durability

Multiverse Level+

Vecna · Dungeons & Dragons · Greater God and boosted By The Serpent

Tier

2-A

Attack Potency

Multiverse Level+

Speed

Infinite

Durability

Multiverse Level+

A heuristic estimate from normalized VS Battles Wiki stats: tier, attack potency, speed and durability.