Viral vs Nephthys: who would win?

Viral favored — Slight edge (~55%)

Viral · Tengen Toppa Gurren Lagann · Post-Apotheosis

Tier
HIGH 1-C
Attack Potency
High Complex Multiverse Level
Speed
Massively Ftl+, up to Infinite
Durability
High Complex Multiverse Level

Nephthys · Toaru Majutsu no Index · Base

Tier
HIGH 1-C
Attack Potency
High Complex Multiverse Level
Speed
Sub-Relativistic
Durability
High Complex Multiverse Level

A heuristic estimate from normalized VS Battles Wiki stats: tier, attack potency, speed and durability.