Shin Nemoto vs Isagi Yoichi: who would win?

Shin Nemoto favored — Slight edge (~55%)

Shin Nemoto · My Hero Academia · Base

Tier
9-C
Attack Potency
Street Level
Speed
Superhuman, up to Supersonic
Durability
Unknown

Isagi Yoichi · Blue Lock · Base

Tier
10-A
Attack Potency
Athlete Level
Speed
Athletic Human
Durability
Street Level

A heuristic estimate from normalized VS Battles Wiki stats: tier, attack potency, speed and durability.