Lololo & Lalala vs Karthus: who would win?

Karthus favored — Slight edge (~55%)

Lololo & Lalala · Kirby · Base

Tier

HIGH 6-A

Attack Potency

Multi-Continent Level

Speed

Below Average Human, up to Relativistic+

Durability

Multi-Continent Level

Karthus · League of Legends · Pentakill Karthus

Tier

HIGH 6-A

Attack Potency

Multi-Continent Level

Speed

Subsonic

Durability

Multi-Continent Level

A heuristic estimate from normalized VS Battles Wiki stats: tier, attack potency, speed and durability.