The Great Intelligence vs Hecatoncheires: who would win?

The Great Intelligence favored — Slight edge (~55%)

The Great Intelligence · Doctor Who · Base

Tier

2-C, up to HIGH 1-C

Attack Potency

Low Multiverse Level, up to High Complex Multiverse Level

Speed

Nigh-Omnipresent

Durability

Low Multiverse Level, up to High Complex Multiverse Level

Hecatoncheires · Dungeons & Dragons · Base

Tier

2-C, up to 2-A

Attack Potency

Low Multiverse Level, up to Multiverse Level+

Speed

Infinite

Durability

Low Multiverse Level, up to Multiverse Level+

A heuristic estimate from normalized VS Battles Wiki stats: tier, attack potency, speed and durability.