Ancient One vs Isu: who would win?

Isu favored — Slight edge (~55%)

Ancient One · Marvel · Base

Tier

8-C, up to LOW 2-C

Attack Potency

Building Level, up to Universe Level+

Speed

Subsonic

Durability

Mountain Level, up to Planet Level

Isu · Assassin's Creed · Technologically

Tier

8-C, up to 5-B

Attack Potency

Building Level, up to Multi-Continent Level

Speed

Hypersonic

Durability

Multi-Continent Level, up to Planet Level

A heuristic estimate from normalized VS Battles Wiki stats: tier, attack potency, speed and durability.